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23 October 2018
Vol 11, Issue 553

About The Cover

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Online Cover This week features a Research Article that describes a complex pathway through which the lipid sphingosine 1-phosphate stimulates the mobilization of a growth factor to drive eyelid closure in the rat embryo. The image shows a cross section of an embryonic rat eye as the eyelid primordia migrate over the cornea. The eyelid primordia eventually fuse to protect the eye during birth and early postnatal development. [Image: Bian et al./Science Signaling]