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In the Current Issue 21 May 2013 (Issue 276)


Research Articles

Estrogen Reduces Lipid Content in the Liver Exclusively from Membrane Receptor Signaling
Ali Pedram, Mahnaz Razandi, Fiona O'Mahony, Harry Harvey, Brian J. Harvey, and Ellis R. Levin
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Eukaryotic G Protein Signaling Evolved to Require G Protein–Coupled Receptors for Activation
William Bradford, Adam Buckholz, John Morton, Collin Price, Alan M. Jones, and Daisuke Urano
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Cross-Species Protein Interactome Mapping Reveals Species-Specific Wiring of Stress Response Pathways
Jishnu Das, Tommy V. Vo, Xiaomu Wei, Joseph C. Mellor, Virginia Tong, Andrew G. Degatano, Xiujuan Wang, Lihua Wang, Nicolas A. Cordero, Nathan Kruer-Zerhusen, Akihisa Matsuyama, Jeffrey A. Pleiss, Steven M. Lipkin, Minoru Yoshida, Frederick P. Roth, and Haiyuan Yu
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Review

Sticky Signaling—Adhesion Class G Protein–Coupled Receptors Take the Stage
Tobias Langenhan, Gabriela Aust, and Jörg Hamann
Gloss  |  Abstract  |  Full Text  |  PDF

Perspective

Understanding the Determinants of Notch Interactions with Its Ligands
Jose F. deCelis
Abstract  |  Full Text  |  PDF

Glossary

Find out what CNA, Mst1, and Sav mean in the world of cell signaling.
New Terms  |  Search and Browse the Glossary

Editors' Choice

Hypoxia Prevents miRNA Processing
J. Shen et al. Nature 497, 383–387 (2013).
Read this Summary  |  Read all Summaries

In Literature

What's Hot
Read this highly accessed article published recently in a previous issue:
Nutrient Signaling in Protein Homeostasis: An Increase in Quantity at the Expense of Quality
Abstract  |  Full Text
Virtual Journal
Check out this article, just added to the Virtual Journal:
Neural Context Reinstatement Predicts Memory Misattribution
Abstract  |  Full Text  |  Search and browse the Virtual Journal
Related to Science
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Featured in Science
Find Science Signaling articles featured in the Editors' Choice section of Science Magazine.
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Issue Archive
Access the table of contents of back issues of Science Signaling (a continuation of Science's STKE).

In Community

Events, Meeting Reports, and Presentations
Check out the calendar, read highlights, and view presentations of cell signaling meetings and conferences.
Directory
Featured person: Lew Jacobson. Find collaborators and people with shared research interests—join the Signaling community and add your information to the Directory!
Forums
Share highlights from signaling meetings or read the recent posting "Linking Cancer and Metabolism" in Meeting Highlights.
E-Letters
Featured E-Letter: Read this pair of comments posted about a Research Resource by Chae et al. Find out how to submit a comment to make Science Signaling a rich community by contributing your knowledge.

In Resources

Teaching Resources
Featuring the course "Systems Biology—Biomedical Modeling," explore this and other materials for teachers.
Glossary
Find out what those acronyms and abbreviations mean. Browse or search the glossary of cell signaling terms. Look at the list of the most recently added terms.
Podcasts
Tune-in for a portable and understandable summary of selected cell signaling research. Check out each episode of the Science Signaling Podcast.
ST NetWatch
Featured in Bioinformatics Resources: cBio Cancer Genomics Portal. Explore the sites selected by the editors or submit your favorite signal transduction Web site.
Funding Sources
Check out the opportunities for funding cell signaling research and training.
Jobs
Search or browse employment opportunities related to signal transduction in Science Careers.

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