Resources Complementing Science Magazine: 2004

Prior to January 2008, Science Signaling was published as Science's STKE. Focus Issues and individual articles were published in conjunction with Science Special Issues. Below you will find a list of the articles and resources that complement particular issues or articles in Science for 2004.

2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001

Science Special Issue: Cell Signaling (26 November 2004)

Editorial Guide

• N. R. Gough, E. M. Adler, L. B. Ray, Focus issue—Cell Signaling—Making New Connections. Sci. STKE 2004, eg12 (2004). [Summary] [Full Text]

Science Special Issue: Genes in Action (22 October 2004)

Editorial Guide

• N. R. Gough, Focus issue—The dynamics of gene expression. Sci. STKE 2004, eg11 (2004). [Summary] [Full Text]

Perspective

• A. M. Fowler, E. T. Alarid, Dynamic control of nuclear receptor transcription. Sci. STKE 2004, pe51 (2004). [Summary] [Full Text]

Review

• J. Z. Dalgaard, S. Vengrova, Selective gene expression in multigene families from yeast to mammals. Sci. STKE 2004, re17 (2004). [Gloss] [Abstract] [Full Text]

Protocols

• A. K. Nagaich, G. L. Hager, UV laser crosslinking: A real-time assay to study dynamic protein/DNA interactions during chromatin remodeling. Sci. STKE 2004, pl13 (2004). [Abstract] [Full Text]

Science Special Issue: Cognition & Behavior (15 October 2004)

Editorial Guide

• E. M. Adler, N. R. Gough, Focus issue—Signals along a road to the mind? Sci. STKE 2004, eg10 (2004). [Summary] [Full Text]

Perspective

• A. Pollack, Coactivation of D1 and D2 dopamine receptors: In marriage, a case of his, hers, and theirs. Sci. STKE 2004, pe50 (2004). [Summary] [Full Text]

Review

• S. G. Cull-Candy, D. N. Leszkiewicz, Role of distinct NMDA receptor subtypes at central synapses. Sci. STKE 2004, re16 (2004). [Gloss] [Abstract] [Full Text]

Science Special Issue: Piecing Together Human Aging (3 September 2004)

Review

• M. Hughes-Fulford, Signal transduction and mechanical stress. Sci. STKE 2004, re12 (2004). [Gloss] [Abstract] [Full Text]

Science Special Issue: Testing Human Limits (30 July 2004)

Perspective

• D. J. Handelsman, Designer androgens in sport: When Too Much Is Never Enough. Sci. STKE 2004, pe41 (2004). [Summary] [Full Text]

Review

• V. Sartorelli, M. Fulco, Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy. Sci. STKE 2004, re11 (2004). [Abstract] [Full Text]

Science Special Issue: Immunotherapy (9 July 2004)

Editorial Guide

• E. M. Adler, Focus issue—Tailoring the immune response. Sci. STKE 2004, eg9 (2004). [Summary] [Full Text]

Perspectives

• E. G. Engleman, J. Brody, L. Soares, Using signaling pathways to overcome immune tolerance to tumors. Sci. STKE 2004, pe28 (2004). [Summary] [Full Text]
• V. Heissmeyer, A. Rao, E3 ligases in T cell anergy—Turning immune responses into tolerance. Sci. STKE 2004, pe29 (2004). [Summary] [Full Text]
• A. J. Olszewski, M. L. Grossbard, Empowering targeted therapy: Lessons from rituximab. Sci. STKE 2004, pe30 (2004). [Summary] [Full Text]

Science Special Issue: Drug Discovery (19 March 2004)

Editorial Guide

• N. R. Gough, E. M. Adler, L. B. Ray, Focus issue—Targeting signaling pathways for drug discovery Sci. STKE 2004, eg5 (2004). [Summary] [Full Text]

Perspectives

• W. G. Kaelin, Jr., Gleevec: Prototype or outlier? Sci. STKE 2004, pe12 (2004). [Summary] [Full Text]
• M. R. Philips, Methotrexate and Ras methylation: A new trick for an old drug? Sci. STKE 2004, pe13 (2004). [Summary] [Full Text]
• B. Shen, Accessing natural products by combinatorial biosynthesis. Sci. STKE 2004, pe14 (2004). [Summary] [Full Text]

Review

• D. S. Charney, H. K. Manji, Life stress, genes, and depression: Multiple pathways lead to increased risk and new opportunities for intervention. Sci. STKE 2004, re5 (2004). [Abstract] [Full Text]

Science Special Issue: Evolution of Language (27 February 2004)

Editorial Guide

• L. B. Ray, N. R. Gough, Focus issue—Evolution of language. Sci. STKE 2004, eg4 (2004). [Summary] [Full Text]

Perspectives

• M. I. Aladjem, S. Pasa, S. Parodi, J. N. Weinstein, Y. Pommier, K. W. Kohn, Molecular interaction maps—A diagrammatic graphical language for bioregulatory networks. Sci. STKE 2004, pe8 (2004). [Summary] [Full Text][Cell Cycle eMIMs]
• B. R. Franza, From play to laws: Language in biology. Sci. STKE 2004, pe9 (2004). [Summary] [Full Text]

Connections Maps

• Connections Maps Database [Pathways]
• Connections Maps Help and Description [Full Text]

Science Special Issue: Mathematics in Biology (6 February 2004)

Editorial Guide

• L. B. Ray, E. M. Adler, N. R. Gough, L. D. Chong, Focus issue—Computational approaches in signal transduction. Sci. STKE 2004, eg3 (2004). [Summary] [Full Text]

Review

• S. Sukharev, D. P. Corey, Mechanosensitive channels: Multiplicity of families and gating paradigms. Sci. STKE 2004, re4 (2004). [Gloss][Abstract] [Full Text]

Protocols

• T. Kortemme, D. E. Kim, D. Baker, Computational alanine scanning of protein-protein interfaces. Sci. STKE 2004, pl2 (2004). [Abstract] [Full Text]
• B. Kutscher, P. Devreotes, P. A. Iglesias, Local excitation, global inhibition mechanism for gradient sensing: An interactive applet. Sci. STKE 2004, pl3 (2004). [Abstract] [Full Text][Applet]
• S. J. Vayttaden, U. S. Bhalla, Developing complex signaling models using GENESIS/Kinetikit. Sci. STKE 2004, pl4 (2004). [Abstract] [Full Text][Software and Demos]
• R. Yasuda, E. A. Nimchinsky, V. Scheuss, T. A. Pologruto, T. G. Oertner, B. L. Sabatini, K. Svoboda, Imaging calcium concentration dynamics in small neuronal compartments. Sci. STKE 2004, pl5 (2004). [Abstract] [Full Text]

Forum

• Open Discussion of Modeling and Computational Approaches to Cellular Signaling. [Discussion]

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