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Resources Complementing Science Magazine: 2011

Prior to January 2008, Science Signaling was published as Science's STKE. Focus Issues and individual articles were published in conjunction with Science Special Issues. Below you will find a list of the articles and resources that complement particular issues or articles in Science for 2011.

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Science Special Issue: Cancer Crusade at 40 (25 March 2011)

Editorial Guide

  • E. M. Adler, N. R. Gough, Focus Issue: Rendering resistance futile. Sci. Signal. 4, eg3 (2011). [Abstract] [Full Text]

Perspectives

  • S. Ganesan, MYC, PARP1, and chemoresistance: BIN there, done that? Sci. Signal. 4, pe15 (2011). [Abstract] [Full Text] [PDF]
  • P. I. Poulikakos, D. B. Solit, Resistance to MEK inhibitors: Should we co-target upstream? Sci. Signal. 4, pe16 (2011). [Abstract] [Full Text] [PDF]

Research Articles

  • A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. Cook, Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells. Sci. Signal. 4, ra17 (2011). [Abstract] [Full Text] [PDF]
  • S. Pyndiah, S. Tanida, K. M. Ahmed, E. K. Cassimere, C. Choe, D. Sakamuro, c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: A mechanism by which cancer cells acquire cisplatin resistance. Sci. Signal. 4, ra19 (2011). [Abstract] [Full Text] [PDF]
  • L. Rubbi, B. Titz, L. Brown, E. Galvan, E. Komisopoulou, S. S. Chen, T. Low, M. Tahmasian, B. Skaggs, M. M�schen, M. Pellegrini, T. G. Graeber, Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling. Sci. Signal. 4, ra18 (2011). [Abstract] [Full Text] [PDF]

Podcast

  • T. G. Graeber, A. M. VanHook, Science Signaling Podcast: 29 March 2011. Sci. Signal. 4, pc6 (2011). [Abstract] [Transcript] [Podcast]

Science Special Issue: Dealing with Data (11 February 2011)

Editorial Guide

  • N. R. Gough, M. B. Yaffe, Focus Issue: Conquering the data mountain. Sci. Signal. 4, eg2 (2011). [Abstract] [Full Text]

Perspectives

  • J. V. Olsen, M. Mann, Effective representation and storage of mass spectrometry–based proteomic data sets for the scientific community. Sci. Signal. 4, pe7 (2011). [Abstract] [Full Text]
  • J. Saez-Rodriguez, L. G. Alexopoulos, G. Stolovitzky, Setting the standards for signal transduction research. Sci. Signal. 4, pe10 (2011). [Abstract] [Full Text]
  • F. M. White, The potential cost of high-throughput proteomics. Sci. Signal. 4, pe8 (2011). [Abstract] [Full Text]
  • H. S. Wiley, Integrating multiple types of data for signaling research: Challenges and opportunities. Sci. Signal. 4, pe9 (2011). [Abstract] [Full Text]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882