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Resources Complementing Science Magazine: 2012

Prior to January 2008, Science Signaling was published as Science's STKE. Focus Issues and individual articles were published in conjunction with Science Special Issues. Below you will find a list of the articles and resources that complement particular issues or articles in Science for 2012.

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Science Special Issue: Depression (5 October 2012)


  • M. M. Shah, HCN1 channels: A new therapeutic target for depressive disorders? Sci. Signal. 5, pe44 (2012). [Abstract] [Full Text] [PDF]
  • H. Anisman, S. Hayley, Inflammatory factors contribute to depression and its comorbid conditions. Sci. Signal. 5, pe45 (2012). [Abstract] [Full Text] [PDF]

Science Special Issue: Computational Biology (13 April 2012)

Editorial Guide

  • W. Wong, J.F. Foley, Focus Issue: Adding Math to the Signaling Toolkit. Sci. Signal. 5, eg5 (2012). [Abstract] [Full Text]

Research Articles

  • M. Matsuda, M. Koga, E. Nishida, M. Ebisuya, Synthetic signal propagation through direct cell-cell interaction. Sci. Signal. 5, ra31 (2012). [Abstract] [Full Text] [PDF]
  • D. J. Klinke II, N. Cheng, E. Chambers, Quantifying crosstalk among interferon-γ, interleukin-12, and tumor necrosis factor signaling pathways within a TH1 cell model. Sci. Signal. 5, ra32 (2012). [Abstract] [Full Text] [PDF]


  • R. K. Das, A. H. Mao, R. V. Pappu, Unmasking functional motifs within disordered regions of proteins. Sci. Signal. 5, pe17 (2012). [Abstract] [Full Text] [PDF]
  • A. L. Slusarczyk, R. Weiss, Understanding signaling dynamics through synthesis. Sci. Signal. 5, pe16 (2012). [Abstract] [Full Text] [PDF]


  • B. Kholodenko, M. B. Yaffe, W. Kolch, Computational approaches for analyzing information flow in biological networks. Sci. Signal. 5, re1 (2012). [Gloss] [Abstract] [Full Text] [PDF]


  • Y. Li, R. J. Arsenault, B. Trost, J. Slind, P. J. Griebel, S. Napper, A. Kusalik, A systematic approach for analysis of peptide array kinome data. Sci. Signal. 5, pl2 (2012). [Abstract] [Full Text] [PDF]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882