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Sci. Signal., 15 December 2009
Vol. 2, Issue 101, p. pe78
[DOI: 10.1126/scisignal.2101pe78]

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Cell Mechanics and Feedback Regulation of Actomyosin Networks

Rodrigo Fernandez-Gonzalez and Jennifer A. Zallen*

Howard Hughes Medical Institute and the Developmental Biology Program, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.

Abstract: Actomyosin contractility is the major force-generating machinery that shapes cells and tissues during morphogenesis. New evidence from Drosophila demonstrates that these forces are spatially organized by a combination of biochemical and mechanical signals that provide dynamic feedback in a complex cellular environment.

* Corresponding author. E-mail, zallenj{at}mskcc.org.

Citation: R. Fernandez-Gonzalez, J. A. Zallen, Cell Mechanics and Feedback Regulation of Actomyosin Networks. Sci. Signal. 2, pe78 (2009).

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