Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Sci. Signal., 6 January 2009
Vol. 2, Issue 52, p. pe2
[DOI: 10.1126/scisignal.151pe55]

PERSPECTIVES

Computational Implications of Cooperative Plasticity Induction at Nearby Dendritic Sites

Kenji Morita*

RIKEN Brain Science Institute (Wako, Japan).

Abstract: Recent studies have revealed that plasticity is not regulated independently at individual synapses but rather that there is cooperativity or associativity between nearby synapses in the dendritic tree of individual cortical pyramidal cells. Here, I summarize experimental results regarding such cooperative plasticity and its underlying mechanisms and consider their computational implications.

* Corresponding author. E-mail, morita{at}brain.riken.jp

Citation: K. Morita, Computational Implications of Cooperative Plasticity Induction at Nearby Dendritic Sites. Sci. Signal. 2, pe2 (2009).

Read the Full Text

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882