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Sci. STKE, 18 December 2001
Vol. 2001, Issue 113, p. pe43
[DOI: 10.1126/stke.2001.113.pe43]

MEETING REPORTS

Meeting Report: Signaling Schemes for TGF-ß

Anita B. Roberts1* and Rik Derynck2

1The Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, Bethesda, MD 20892-5055, USA.
2The Department of Growth and Development, Program in Cell Biology, University of California at San Francisco, San Francisco, CA 94143-0640, USA.

A review of the meeting "The TGF-ß Superfamily: Signaling and Development," FASEB Summer Research Conference, Tucson, Arizona, 7 to 12 July 2001.

Summary: The transforming growth factor-ß (TGF-ß) superfamily of signaling molecules regulates many developmental processes in a range of organisms from worms to humans. Understanding the mechanisms by which they exert their repertoire of effects has required identification of the components of signaling pathways that they control. Roberts and Derynck focus on this aspect of TGF-ß biology in their review of a recent Federation of American Societies for Experimental Biology (FASEB) meeting on TGF-ß signaling and development and summarize current signaling paradigms and future prospects in TGF-ß signaling from the cell surface to the nucleus.

*Corresponding author. E-mail:robertsa{at}dce41.nci.nih.gov

Citation: A. B. Roberts, R. Derynck, Meeting Report: Signaling Schemes for TGF-ß. Sci. STKE 2001, pe43 (2001).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882