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Sci. STKE, 5 November 2002 EDITORS' CHOICEMITOCHONDRIA Protecting the HeartWithin the mitochondria of heart cells, ion channels control the flux of different ions and change the physiological status of the mitochondria, which in turn affect the relative health of the heart cell. Xu et al. now describe the role of a calcium-activated potassium channel in the inner mitochondrial membrane of guinea-pig heart cells in protecting the cells from ischemia. A drug that opened the channel could protect the heart from infarction. W. Xu, Y. Liu, S. Wang, T. McDonald, J. E. Van Eyk, A. Sidor, B. O'Rourke, Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane. Science 298, 1029-1033 (2002). [Abstract] [Full Text]
Citation: Protecting the Heart. Sci. STKE 2002, tw405 (2002). The editors suggest the following Related Resources on Science sites:In Science Magazine
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