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Sci. STKE, 1 March 2005
Vol. 2005, Issue 273, p. pe8
Swapping Molecules During Cell-Cell Interactions
Department of Immunology, IMM4, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Interactions between cells of the immune system can lead to intercellular exchange of cell-surface molecules. Recent studies indicate that such exchange can be bidirectional when natural killer cells interact with their target cells. Sprent reviews the mechanisms involved in cell-cell molecular transfer and the receptor-ligand interactions involved.