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Sci. STKE, 15 March 2005
Vol. 2005, Issue 275, p. pe11
[DOI: 10.1126/stke.2752005pe11]

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Alone at Last! New Functions for Ca2+ Channel ß Subunits?

Matthieu Rousset, Thierry Cens, and Pierre Charnet*

Neurobiologie Moléculaire, CRBM FRE 2593, CNRS, 1919 Route de Mende, 34293 Montpellier Cedex, France.

Summary: New functions for voltage-gated Ca2+ channel auxiliary ß subunits have recently been identified. These functions appear to be regulated by the ß subunit alone, independently of any effects on the Ca2+ influx; hence, the ß subunit may not be truly "auxiliary" and may play more fundamental roles in Ca2+ homeostasis or gene regulation. These new findings raise important questions and open new, exciting research avenues.

*Corresponding author. E-mail: pierre.charnet{at}crbm.cnrs.fr

Citation: M. Rousset, T. Cens, P. Charnet, Alone at Last! New Functions for Ca2+ Channel ß Subunits? Sci. STKE 2005, pe11 (2005).

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