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Sci. Signal., 5 October 2010
Vol. 3, Issue 142, p. pc18
[DOI: 10.1126/scisignal.3142pc18]


Science Signaling Podcast: 5 October 2010

Dirk M. Hermann1 and Annalisa M. VanHook2

1 Department of Neurology, University Hospital Essen, Germany.
2 Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This is a conversation with Dirk Hermann about a Research Article published in the 5 October 2010 issue of Science Signaling. ElAli and Hermann report that apolipoprotein E (ApoE) regulates ATP-binding cassette (ABC) drug transporters in the ischemic brain, thereby controlling brain-to-blood drug distribution. Inhibition of ApoE signaling is a potential clinical strategy for enhancing the delivery of neuroprotective drugs to the brain after ischemic stroke.

Citation: D. M. Hermann, A. M. VanHook, Science Signaling Podcast: 5 October 2010. Sci. Signal. 3, pc18 (2010).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882