Sci. Signal., 5 April 2011
Science Signaling Podcast: 5 April 2011
Sophie Ugolini1,2,3, Eric Vivier1,2,3,4, and Annalisa M. VanHook5
1 Centre dImmunologie de Marseille-Luminy, Université de la Méditerranée, Campus de Luminy case 906, 13288 Marseille, France.
Abstract: This Podcast features a conversation with the senior authors of a Research Article published in the April 5 issue of Science Signaling. Sophie Ugolini and Eric Vivier discuss their teams finding that signaling through inhibitory NK cell receptors determines the distribution of activating receptors, which, in turn, determines the responsiveness of the cells to activating stimuli. This finding suggests that inhibitory receptors can affect membrane receptor organization and hence the responsiveness of NK cells.
Citation: S. Ugolini, E. Vivier, A. M. VanHook, Science Signaling Podcast: 5 April 2011. Sci. Signal. 4, pc7 (2011).
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