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Sci. Signal., 15 January 2013
Vol. 6, Issue 258, p. eg2
[DOI: 10.1126/scisignal.2003938]


Focus Issue: Understanding Mechanisms of Inflammation

John F. Foley1*

1 Senior Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005, USA.

Abstract: This Focus Issue of Science Signaling, which complements the Science Special Issue on Inflammation, includes research that reveals regulators of a receptor implicated in an inflammatory bowel disease, as well as the contribution of a matrix metalloproteinase to skin inflammation. Perspectives discuss the role of proinflammatory cytokines in brain inflammatory disorders and the regulation of multiple types of cell death in tissues in response to proinflammatory factors. Together with content from the Science Signaling Archives, these articles underline the importance of understanding the basis of inflammatory responses that can both protect and harm the host.

* Corresponding author. E-mail: jfoley{at}

Citation: J. F. Foley, Focus Issue: Understanding Mechanisms of Inflammation. Sci. Signal. 6, eg2 (2013).

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