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Sci. Signal., 16 April 2013
Vol. 6, Issue 271, p. tr5
[DOI: 10.1126/scisignal.2003450]


Coupled Transport Protein Systems

Jack D. Thatcher*

West Virginia School of Osteopathic Medicine, 400 North Lee Street, Lewisburg, WV 24901, USA.

Abstract: This set of animated lessons provides examples of how transport proteins interact in coupled systems to produce physiologic effects. The gastric pumps animation depicts the secretion of hydrochloric acid into the gastric lumen. The animation called glucose absorption depicts glucose absorption by intestinal epithelial cells. The CFTR animation explains how the cystic fibrosis conductance transmembrane regulator (CFTR) functions as a key component of a coupled system of transport proteins that clears the pulmonary system of mucus and inhaled particulates. These animations serve as valuable resources for any collegiate-level course that describes these processes. Courses that might use them include introductory biology, biochemistry, biophysics, cell biology, pharmacology, and physiology.

* Corresponding author. E-mail: jthatcher{at}

Citation: J. D. Thatcher, Coupled Transport Protein Systems. Sci. Signal. 6, tr5 (2013).

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