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Sci. STKE, 30 April 2002
Vol. 2002, Issue 130, p. pe20
[DOI: 10.1126/stke.2002.130.pe20]

PERSPECTIVES

Opening Pandora's Box: Clinical Data and the Study of Complex Diseases

Michael N. Liebman*

Computational Biology, Abramson Family Cancer Research Center, University of Pennsylvania Cancer Center, Philadelphia, PA 19104-6160, USA.

Summary: Complex diseases have complex phenotypes, and proper diagnosis requires that the analysis take into account the patient's history and exposure to environmental factors, as well as genetic information. Signaling information is one aspect of a grander "biomedical informatics" approach advocated for a better understanding of a patient's medically relevant disease phenotype.

*Contact information: Telephone, 215-746-5570; fax, 215-573-2486; e-mail, liebmanm{at}mail.med.upenn.edu

Citation: M. N. Liebman, Opening Pandora's Box: Clinical Data and the Study of Complex Diseases. Sci. STKE 2002, pe20 (2002).

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Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)