Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Logo for

PLANT CELL 14 (12): 3163-3176

Copyright © 2002 by the American Society of Plant Physiologists.

Cloning the Tomato Curl3 Gene Highlights the Putative Dual Role of the Leucine-Rich Repeat Receptor Kinase tBRI1/SR160 in Plant Steroid Hormone and Peptide Hormone Signaling

Teresa Montoya1,a, Takahito Nomura1,a,b, Kerrie Farrara, Tsuyoshi Kanetac, Takao Yokotab, and Gerard J. Bishop2,a

a Institute of Biological Sciences, University of Wales Aberystwyth, Aberystwyth SY23 3DA, United Kingdom
b Department of Biosciences, Teikyo University, Utsunomiya 320-8551, Japan
c Department of Biology and Earth Sciences, Faculty of Science, Ehime University, Matsuyama 790-8577, Japan

2 To whom correspondence should be addressed. E-mail gdb{at}; fax 44-(0)1970-622350

Abstract: Brassinosteroids (BRs) are plant steroid hormones that are essential for normal plant development. To gain better understanding of the conservation of BR signaling, the partially BR-insensitive tomato mutant altered brassinolide sensitivity1 (abs1) was identified and found to be a weak allele at the curl3 (cu3) locus. BR content is increased in both of these mutants and is associated with increased expression of Dwarf. The tomato homolog of the Arabidopsis Brassinosteroid Insensitive1 Leu-rich repeat (LRR) receptor-like kinase, named tBri1, was isolated using degenerate primers. Sequence analysis of tBRI1 in the mutants cu3 and abs1 revealed that cu3 is a nonsense mutant and that abs1 is a missense mutant. A comparison of BRI1 homolog sequences highlights conserved features of BRI1 sequences, with the LRRs in close proximity to the island domain showing more conservation than N-terminal LRRs. The most homologous sequences were found in the kinase and transmembrane regions. tBRI1 (SR160) also has been isolated as the putative receptor for systemin, a plant peptide hormone. This finding suggests a possible dual role for tBRI1 in steroid hormone and peptide hormone signaling.

Identification and Functional Analysis of Tomato BRI1 and BAK1 Receptor Kinase Phosphorylation Sites.
V. S. Bajwa, X. Wang, R. K. Blackburn, M. B. Goshe, S. K. Mitra, E. L. Williams, G. J. Bishop, S. Krasnyanski, G. Allen, S. C. Huber, et al. (2013)
Plant Physiology 163, 30-42
   Abstract »    Full Text »    PDF »
Brassinosteroid biosynthesis and signalling in Petunia hybrida.
N. Verhoef, T. Yokota, K. Shibata, G.-J. de Boer, T. Gerats, M. Vandenbussche, R. Koes, and E. Souer (2013)
J. Exp. Bot. 64, 2435-2448
   Abstract »    Full Text »    PDF »
The Shoot Apical Meristem Regulatory Peptide CLV3 Does Not Activate Innate Immunity.
C. Segonzac, Z. L. Nimchuk, M. Beck, P. T. Tarr, S. Robatzek, E. M. Meyerowitz, and C. Zipfel (2012)
PLANT CELL 24, 3186-3192
   Abstract »    Full Text »    PDF »
Brassinosteroid Signal Transduction: From Receptor Kinase Activation to Transcriptional Networks Regulating Plant Development.
S. D. Clouse (2011)
PLANT CELL 23, 1219-1230
   Abstract »    Full Text »    PDF »
Plant Phosphatidylcholine-Hydrolyzing Phospholipases C NPC3 and NPC4 with Roles in Root Development and Brassinolide Signaling in Arabidopsis thaliana.
R. Wimalasekera, P. Pejchar, A. Holk, J. Martinec, and G. F. E. Scherer (2010)
Mol Plant 3, 610-625
   Abstract »    Full Text »    PDF »
HORMONOMETER: A Tool for Discerning Transcript Signatures of Hormone Action in the Arabidopsis Transcriptome.
D. Volodarsky, N. Leviatan, A. Otcheretianski, and R. Fluhr (2009)
Plant Physiology 150, 1796-1805
   Abstract »    Full Text »    PDF »
Reactive Oxygen Species Are Involved in Brassinosteroid-Induced Stress Tolerance in Cucumber.
X.-J. Xia, Y.-J. Wang, Y.-H. Zhou, Y. Tao, W.-H. Mao, K. Shi, T. Asami, Z. Chen, and J.-Q. Yu (2009)
Plant Physiology 150, 801-814
   Abstract »    Full Text »    PDF »
A cotton gene encoding a polygalacturonase inhibitor-like protein is specifically expressed in petals.
H. Shi, L. Zhu, Y. Zhou, G. Li, L. Chen, and X. Li (2009)
Acta Biochim Biophys Sin 41, 316-324
   Abstract »    Full Text »    PDF »
Expression of the SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 (SERK1) gene is associated with developmental change in the life cycle of the model legume Medicago truncatula.
K. E. Nolan, S. Kurdyukov, and R. J. Rose (2009)
J. Exp. Bot. 60, 1759-1771
   Abstract »    Full Text »    PDF »
Xanthomonas T3S Effector XopN Suppresses PAMP-Triggered Immunity and Interacts with a Tomato Atypical Receptor-Like Kinase and TFT1.
J.-G. Kim, X. Li, J. A. Roden, K. W. Taylor, C. D. Aakre, B. Su, S. Lalonde, A. Kirik, Y. Chen, G. Baranage, et al. (2009)
PLANT CELL 21, 1305-1323
   Abstract »    Full Text »    PDF »
Diverse Transcriptional Programs Associated with Environmental Stress and Hormones in the Arabidopsis Receptor-Like Kinase Gene Family.
L. Chae, S. Sudat, S. Dudoit, T. Zhu, and S. Luan (2009)
Mol Plant 2, 84-107
   Abstract »    Full Text »    PDF »
The Arabidopsis Kinase-Associated Protein Phosphatase Regulates Adaptation to Na+ Stress.
Y. Manabe, R. A. Bressan, T. Wang, F. Li, H. Koiwa, I. Sokolchik, X. Li, and A. Maggio (2008)
Plant Physiology 146, 612-622
   Abstract »    Full Text »    PDF »
Micro-Electrode Flux Estimation Confirms That the Solanum pimpinellifolium cu3 Mutant Still Responds to Systemin.
F. C. Lanfermeijer, M. Staal, R. Malinowski, J. W. Stratmann, and J. T. M. Elzenga (2008)
Plant Physiology 146, 129-139
   Abstract »    Full Text »    PDF »
Tomato BRASSINOSTEROID INSENSITIVE1 Is Required for Systemin-Induced Root Elongation in Solanum pimpinellifolium but Is Not Essential for Wound Signaling.
N. Holton, A. Cano-Delgado, K. Harrison, T. Montoya, J. Chory, and G. J. Bishop (2007)
PLANT CELL 19, 1709-1717
   Abstract »    Full Text »    PDF »
Plant hormone receptors: perception is everything.
B. Chow and P. McCourt (2006)
Genes & Dev. 20, 1998-2008
   Abstract »    Full Text »    PDF »
Morphological Alteration Caused by Brassinosteroid Insensitivity Increases the Biomass and Grain Production of Rice.
Y. Morinaka, T. Sakamoto, Y. Inukai, M. Agetsuma, H. Kitano, M. Ashikari, and M. Matsuoka (2006)
Plant Physiology 141, 924-931
   Abstract »    Full Text »    PDF »
SHR5: a novel plant receptor kinase involved in plant-N2-fixing endophytic bacteria association.
F. Vinagre, C. Vargas, K. Schwarcz, J. Cavalcante, E. M. Nogueira, J. I. Baldani, P. C. G. Ferreira, and A. S. Hemerly (2006)
J. Exp. Bot. 57, 559-569
   Abstract »    Full Text »    PDF »
The Role of OsBRI1 and Its Homologous Genes, OsBRL1 and OsBRL3, in Rice.
A. Nakamura, S. Fujioka, H. Sunohara, N. Kamiya, Z. Hong, Y. Inukai, K. Miura, S. Takatsuto, S. Yoshida, M. Ueguchi-Tanaka, et al. (2006)
Plant Physiology 140, 580-590
   Abstract »    Full Text »    PDF »
Brassinosteroid Homeostasis in Arabidopsis Is Ensured by Feedback Expressions of Multiple Genes Involved in Its Metabolism.
K. Tanaka, T. Asami, S. Yoshida, Y. Nakamura, T. Matsuo, and S. Okamoto (2005)
Plant Physiology 138, 1117-1125
   Abstract »    Full Text »    PDF »
Identification of brassinosteroid-related genes by means of transcript co-response analyses.
J. Lisso, D. Steinhauser, T. Altmann, J. Kopka, and C. Mussig (2005)
Nucleic Acids Res. 33, 2685-2696
   Abstract »    Full Text »    PDF »
The Last Reaction Producing Brassinolide Is Catalyzed by Cytochrome P-450s, CYP85A3 in Tomato and CYP85A2 in Arabidopsis.
T. Nomura, T. Kushiro, T. Yokota, Y. Kamiya, G. J. Bishop, and S. Yamaguchi (2005)
J. Biol. Chem. 280, 17873-17879
   Abstract »    Full Text »    PDF »
BRL1 and BRL3 are novel brassinosteroid receptors that function in vascular differentiation in Arabidopsis.
A. Cano-Delgado, Y. Yin, C. Yu, D. Vafeados, S. Mora-Garcia, J.-C. Cheng, K. H. Nam, J. Li, and J. Chory (2004)
Development 131, 5341-5351
   Abstract »    Full Text »    PDF »
Brassinosteroid Deficiency Due to Truncated Steroid 5{alpha}-Reductase Causes Dwarfism in the lk Mutant of Pea.
T. Nomura, C. E. Jager, Y. Kitasaka, K. Takeuchi, M. Fukami, K. Yoneyama, Y. Matsushita, H. Nyunoya, S. Takatsuto, S. Fujioka, et al. (2004)
Plant Physiology 135, 2220-2229
   Abstract »    Full Text »    PDF »
Plant Hormone Binding Sites.
R. NAPIER (2004)
Ann. Bot. 93, 227-233
   Abstract »    Full Text »    PDF »
LRR-containing receptors regulating plant development and defense.
A. Dievart and S. E. Clark (2004)
Development 131, 251-261
   Abstract »    Full Text »    PDF »
Systemins: A functionally defined family of peptide signals that regulate defensive genes in Solanaceae species.
C. A. Ryan and G. Pearce (2003)
PNAS 100, 14577-14580
   Abstract »    Full Text »
Brassinosteroids Promote Root Growth in Arabidopsis.
C. Mussig, G.-H. Shin, and T. Altmann (2003)
Plant Physiology 133, 1261-1271
   Abstract »    Full Text »    PDF »
A Semidwarf Phenotype of Barley uzu Results from a Nucleotide Substitution in the Gene Encoding a Putative Brassinosteroid Receptor.
M. Chono, I. Honda, H. Zeniya, K. Yoneyama, D. Saisho, K. Takeda, S. Takatsuto, T. Hoshino, and Y. Watanabe (2003)
Plant Physiology 133, 1209-1219
   Abstract »    Full Text »    PDF »
Ligand-receptor pairs in plant peptide signaling.
Y. Matsubayashi (2003)
J. Cell Sci. 116, 3863-3870
   Abstract »    Full Text »    PDF »
Generation of systemin signaling in tobacco by transformation with the tomato systemin receptor kinase gene.
J. M. Scheer, G. Pearce, and C. A. Ryan (2003)
PNAS 100, 10114-10117
   Abstract »    Full Text »    PDF »
The crystal structure of polygalacturonase-inhibiting protein (PGIP), a leucine-rich repeat protein involved in plant defense.
A. Di Matteo, L. Federici, B. Mattei, G. Salvi, K. A. Johnson, C. Savino, G. De Lorenzo, D. Tsernoglou, and F. Cervone (2003)
PNAS 100, 10124-10128
   Abstract »    Full Text »    PDF »
Stress Under the Sun: Spotlight on Ultraviolet-B Responses.
C. L. Ballare (2003)
Plant Physiology 132, 1725-1727
   Full Text »    PDF »
Convergent Responses to Stress. Solar Ultraviolet-B Radiation and Manduca sexta Herbivory Elicit Overlapping Transcriptional Responses in Field-Grown Plants of Nicotiana longiflora.
M. M. Izaguirre, A. L. Scopel, I. T. Baldwin, and C. L. Ballare (2003)
Plant Physiology 132, 1755-1767
   Abstract »    Full Text »    PDF »
2002: Signaling Breakthroughs of the Year.
E. M. Adler, N. R. Gough, and L. B. Ray (2003)
Sci. STKE 2003, eg1
   Full Text »    PDF »

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882