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Science 297 (5580): 405-409

Copyright © 2002 by the American Association for the Advancement of Science

A Role for Peroxisomes in Photomorphogenesis and Development of Arabidopsis

Jianping Hu,12 Maria Aguirre,12 Charles Peto,3 José Alonso,1 Joseph Ecker,1 Joanne Chory12*

The nuclear protein DET1 is a central repressor of photomorphogenesis in plants. We have identified the molecular lesion in ted3, a mutation that dominantly suppresses the phenotypes of det1-1. TED3 encodes a peroxisomal protein (AtPex2p) essential for Arabidopsis growth. Developmental defects and the abnormal expression of many genes in det1 are rescued by ted3. ted3 also partially suppresses another pleiotropic de-etiolated mutant cop1. Thus, peroxisomes, whose functions are still largely unexplored, play a key role in a photomorphogenetic pathway negatively regulated by the DET1 and COP proteins.

1 Plant Biology Laboratory,
2 Howard Hughes Medical Institute,
3 Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
*   To whom correspondence should be addressed. E-mail: chory{at}salk.edu

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