Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Logo for

Science 307 (5712): 1111-1113

Copyright © 2005 by the American Association for the Advancement of Science

Positional Signaling Mediated by a Receptor-like Kinase in Arabidopsis

Su-Hwan Kwak, Ronglai Shen, John Schiefelbein*

Abstract: The position-dependent specification of root epidermal cells in Arabidopsis provides an elegant paradigm for cell patterning during development. Here, we describe a new gene, SCRAMBLED (SCM), required for cells to appropriately interpret their location within the developing root epidermis. SCM encodes a receptor-like kinase protein with a predicted extracellular domain of six leucine-rich repeats and an intracellular serine-threonine kinase domain. SCM regulates the expression of the GLABRA2, CAPRICE, WEREWOLF, and ENHANCER OF GLABRA3 transcription factor genes that define the cell fates. Further, the SCM gene is expressed throughout the developing root. Therefore, SCM likely enables developing epidermal cells to detect positional cues and establish an appropriate cell-type pattern.

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109–1048, USA.

* To whom correspondence should be addressed. E-mail: schiefel{at}umich.edu


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Plant Vascular Biology 2013: vascular trafficking.
R. Ursache, J.-o. Heo, and Y. Helariutta (2014)
J. Exp. Bot. 65, 1673-1680
   Abstract »    Full Text »    PDF »
QUIRKY interacts with STRUBBELIG and PAL OF QUIRKY to regulate cell growth anisotropy during Arabidopsis gynoecium development.
C. Trehin, S. Schrempp, A. Chauvet, A. Berne-Dedieu, A.-M. Thierry, J.-E. Faure, I. Negrutiu, and P. Morel (2013)
Development 140, 4807-4817
   Abstract »    Full Text »    PDF »
Tissue-Specific Profiling Reveals Transcriptome Alterations in Arabidopsis Mutants Lacking Morphological Phenotypes.
M. Simon, A. Bruex, R. M. Kainkaryam, X. Zheng, L. Huang, P. J. Woolf, and J. Schiefelbein (2013)
PLANT CELL 25, 3175-3185
   Abstract »    Full Text »    PDF »
Nuclear Trapping Controls the Position-Dependent Localization of CAPRICE in the Root Epidermis of Arabidopsis.
Y. H. Kang, S.-K. Song, J. Schiefelbein, and M. M. Lee (2013)
Plant Physiology 163, 193-204
   Abstract »    Full Text »    PDF »
ERECTA Family Genes Regulate Auxin Transport in the Shoot Apical Meristem and Forming Leaf Primordia.
M.-K. Chen, R. L. Wilson, K. Palme, F. A. Ditengou, and E. D. Shpak (2013)
Plant Physiology 162, 1978-1991
   Abstract »    Full Text »    PDF »
Transcriptional and Functional Classification of the GOLVEN/ROOT GROWTH FACTOR/CLE-Like Signaling Peptides Reveals Their Role in Lateral Root and Hair Formation.
A. Fernandez, A. Drozdzecki, K. Hoogewijs, A. Nguyen, T. Beeckman, A. Madder, and P. Hilson (2013)
Plant Physiology 161, 954-970
   Abstract »    Full Text »    PDF »
HDA18 Affects Cell Fate in Arabidopsis Root Epidermis via Histone Acetylation at Four Kinase Genes.
C. Liu, L.-C. Li, W.-Q. Chen, X. Chen, Z.-H. Xu, and S.-N. Bai (2013)
PLANT CELL 25, 257-269
   Abstract »    Full Text »    PDF »
Nuclear Ribosome Biogenesis Mediated by the DIM1A rRNA Dimethylase Is Required for Organized Root Growth and Epidermal Patterning in Arabidopsis.
Y. Wieckowski and J. Schiefelbein (2012)
PLANT CELL 24, 2839-2856
   Abstract »    Full Text »    PDF »
A Single Amino Acid Substitution in IIIf Subfamily of Basic Helix-Loop-Helix Transcription Factor AtMYC1 Leads to Trichome and Root Hair Patterning Defects by Abolishing Its Interaction with Partner Proteins in Arabidopsis.
H. Zhao, X. Wang, D. Zhu, S. Cui, X. Li, Y. Cao, and L. Ma (2012)
J. Biol. Chem. 287, 14109-14121
   Abstract »    Full Text »    PDF »
Cell Fate in the Arabidopsis Root Epidermis Is Determined by Competition between WEREWOLF and CAPRICE.
S.-K. Song, K. H. Ryu, Y. H. Kang, J. H. Song, Y.-H. Cho, S.-D. Yoo, J. Schiefelbein, and M. M. Lee (2011)
Plant Physiology 157, 1196-1208
   Abstract »    Full Text »    PDF »
WEREWOLF, a Regulator of Root Hair Pattern Formation, Controls Flowering Time through the Regulation of FT mRNA Stability.
E. Seo, J. Yu, K. H. Ryu, M. M. Lee, and I. Lee (2011)
Plant Physiology 156, 1867-1877
   Abstract »    Full Text »    PDF »
JACKDAW controls epidermal patterning in the Arabidopsis root meristem through a non-cell-autonomous mechanism.
H. Hassan, B. Scheres, and I. Blilou (2010)
Development 137, 1523-1529
   Abstract »    Full Text »    PDF »
Steroids are required for epidermal cell fate establishment in Arabidopsis roots.
K. T. Kuppusamy, A. Y. Chen, and J. L. Nemhauser (2009)
PNAS 106, 8073-8076
   Abstract »    Full Text »    PDF »
Evolutionary History and Stress Regulation of Plant Receptor-Like Kinase/Pelle Genes.
M. D. Lehti-Shiu, C. Zou, K. Hanada, and S.-H. Shiu (2009)
Plant Physiology 150, 12-26
   Abstract »    Full Text »    PDF »
The gene regulatory network for root epidermal cell-type pattern formation in Arabidopsis.
J. Schiefelbein, S.-H. Kwak, Y. Wieckowski, C. Barron, and A. Bruex (2009)
J. Exp. Bot. 60, 1515-1521
   Abstract »    Full Text »    PDF »
The MYB23 Gene Provides a Positive Feedback Loop for Cell Fate Specification in the Arabidopsis Root Epidermis.
Y. H. Kang, V. Kirik, M. Hulskamp, K. H. Nam, K. Hagely, M. M. Lee, and J. Schiefelbein (2009)
PLANT CELL 21, 1080-1094
   Abstract »    Full Text »    PDF »
Diverse Transcriptional Programs Associated with Environmental Stress and Hormones in the Arabidopsis Receptor-Like Kinase Gene Family.
L. Chae, S. Sudat, S. Dudoit, T. Zhu, and S. Luan (2009)
Mol Plant 2, 84-107
   Abstract »    Full Text »    PDF »
Receptor-Like Kinase ACR4 Restricts Formative Cell Divisions in the Arabidopsis Root.
I. De Smet, V. Vassileva, B. De Rybel, M. P. Levesque, W. Grunewald, D. Van Damme, G. Van Noorden, M. Naudts, G. Van Isterdael, R. De Clercq, et al. (2008)
Science 322, 594-597
   Abstract »    Full Text »    PDF »
Manganese deficiency alters the patterning and development of root hairs in Arabidopsis.
T. J. Wei Yang, P. J. Perry, S. Ciani, S. Pandian, and W. Schmidt (2008)
J. Exp. Bot. 59, 3453-3464
   Abstract »    Full Text »    PDF »
Cell Identity Mediates the Response of Arabidopsis Roots to Abiotic Stress.
J. R. Dinneny, T. A. Long, J. Y. Wang, J. W. Jung, D. Mace, S. Pointer, C. Barron, S. M. Brady, J. Schiefelbein, and P. N. Benfey (2008)
Science 320, 942-945
   Abstract »    Full Text »    PDF »
Signaling of cell fate determination by the TPD1 small protein and EMS1 receptor kinase.
G. Jia, X. Liu, H. A. Owen, and D. Zhao (2008)
PNAS 105, 2220-2225
   Abstract »    Full Text »    PDF »
Plant development: new models and approaches bring progress.
J. A. Long (2006)
Development 133, 4609-4612
   Abstract »    Full Text »    PDF »
Arabidopsis NRP1 and NRP2 Encode Histone Chaperones and Are Required for Maintaining Postembryonic Root Growth.
Y. Zhu, A. Dong, D. Meyer, O. Pichon, J.-P. Renou, K. Cao, and W.-H. Shen (2006)
PLANT CELL 18, 2879-2892
   Abstract »    Full Text »    PDF »
Functional Conservation of a Root Hair Cell-Specific cis-Element in Angiosperms with Different Root Hair Distribution Patterns.
D. W. Kim, S. H. Lee, S.-B. Choi, S.-K. Won, Y.-K. Heo, M. Cho, Y.-I. Park, and H.-T. Cho (2006)
PLANT CELL 18, 2958-2970
   Abstract »    Full Text »    PDF »
The BAM1/BAM2 Receptor-Like Kinases Are Important Regulators of Arabidopsis Early Anther Development.
C. L.H. Hord, C. Chen, B. J. DeYoung, S. E. Clark, and H. Ma (2006)
PLANT CELL 18, 1667-1680
   Abstract »    Full Text »    PDF »
Molecular Cloning and Characterization of beta-Expansin Gene Related to Root Hair Formation in Barley.
M. Kwasniewski and I. Szarejko (2006)
Plant Physiology 141, 1149-1158
   Abstract »    Full Text »    PDF »
Positional information and mobile transcriptional regulators determine cell pattern in the Arabidopsis root epidermis.
L. Dolan (2006)
J. Exp. Bot. 57, 51-54
   Abstract »    Full Text »    PDF »
Histone acetylation affects expression of cellular patterning genes in the Arabidopsis root epidermis.
C.-R. Xu, C. Liu, Y.-L. Wang, L.-C. Li, W.-Q. Chen, Z.-H. Xu, and S.-N. Bai (2005)
PNAS 102, 14469-14474
   Abstract »    Full Text »    PDF »
STRUBBELIG defines a receptor kinase-mediated signaling pathway regulating organ development in Arabidopsis.
D. Chevalier, M. Batoux, L. Fulton, K. Pfister, R. K. Yadav, M. Schellenberg, and K. Schneitz (2005)
PNAS 102, 9074-9079
   Abstract »    Full Text »    PDF »

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882