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Abstract:
Mass spectrometry is a central analytical technique for proteinresearch and for the study of biomolecules in general. Drivenby the need to identify, characterize, and quantify proteinsat ever increasing sensitivity and in ever more complex samples,a wide range of new mass spectrometry–based analyticalplatforms and experimental strategies have emerged. Here wereview recent advances in mass spectrometry instrumentationin the context of current and emerging research strategies inprotein science.
1 Institute of Molecular Systems Biology, ETH Zurich, CH-8093 Zurich, Switzerland. 2 Faculty of Sciences, University of Zurich, CH-8006 Zurich, Switzerland. 3 Institute for Molecular Systems Biology, Seattle, WA 98103, USA.
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