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Biologically Based Computational Models of High-Level Cognition
Randall C. O'Reilly
Computer models based on the detailed biology of the brain canhelp us understand the myriad complexities of human cognitionand intelligence. Here, we review models of the higher levelaspects of human intelligence, which depend critically on theprefrontal cortex and associated subcortical areas. The pictureemerging from a convergence of detailed mechanistic models andmore abstract functional models represents a synthesis betweenanalog and digital forms of computation. Specifically, the needfor robust active maintenance and rapid updating of informationin the prefrontal cortex appears to be satisfied by bistableactivation states and dynamic gating mechanisms. These mechanismsare fundamental to digital computers and may be critical forthe distinctive aspects of human intelligence.
Department of Psychology, University of Colorado Boulder, Boulder, CO 80309, USA.
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[DOI: 10.1126/science.314.5796.75] |Summary »|PDF »
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