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Science 318 (5847): 68-69

Copyright © 2007 by the American Association for the Advancement of Science

Advances in Cytokinin Signaling

Bruno Müller, and Jen Sheen*

Abstract: Cytokinins are essential plant hormones that control various processes in plants' development and response to external stimuli. The Arabidopsis cytokinin signal transduction pathway involves hybrid histidine protein kinase sensors, phosphotransfer proteins, and regulators as transcription activators and repressors in a phosphorelay system. Each step is executed by components encoded by multigene families. Recent findings have revealed new functions, new feedback loops, and connections to other signaling pathways.

Department of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.

* To whom correspondence should be addressed. E-mail: sheen{at}molbio.mgh.harvard.edu

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