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Science 318 (5850): 643-645

Copyright © 2007 by the American Association for the Advancement of Science

Changes in Regulation of a Transcription Factor Lead to Autogamy in Cultivated Tomatoes

Kai-Yi Chen,1,2*{dagger} Bin Cong,1,2* Rod Wing,3 Julia Vrebalov,4 Steven D. Tanksley1,2{ddagger}

Abstract: We report the cloning of Style2.1, the major quantitative trait locus responsible for a key floral attribute (style length) associated with the evolution of self-pollination in cultivated tomatoes. The gene encodes a putative transcription factor that regulates cell elongation in developing styles. The transition from cross-pollination to self-pollination was accompanied, not by a change in the STYLE2.1 protein, but rather by a mutation in the Style2.1 promoter that results in a down-regulation of Style2.1 expression during flower development.

1 Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA.
2 Department of Plant Biology, Cornell University, Ithaca, NY 14853, USA.
3 Department of Plant Sciences, Arizona Genomics Institute, University of Arizona, Tucson, AZ 85721, USA.
4 U.S. Department of Agriculture, Agricultural Research Service, Plant, Soil, Nutrition Lab and Boyce Thompson Institute for Plant Research, Cornell University, Ithaca, NY 14853, USA.

* These authors contributed equally to this work

{dagger} Present address: National Taiwan University, Department of Agronomy, Taipei 10617, Taiwan.

{ddagger} To whom correspondence should be addressed. E-mail: sdt4{at}

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