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Sci. Signal., 8 January 2008
Vol. 1, Issue 1, p. eg1
[DOI: 10.1126/stke.11eg1]


2007: Signaling Breakthroughs of the Year

Elizabeth M. Adler1*, John F. Foley1, Nancy R. Gough2, and L. Bryan Ray3

1Associate Editors of Science Signaling,
2Editor of Science Signaling,
3Consulting Editor of Science Signaling and Senior Editor of Science, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This year's notable advances in cell signaling span research into the signals that regulate the state of chromatin in the cell nucleus to those signals that modulate the social behavior of organisms. This year’s findings include unexpected mechanisms and players in immune signaling pathways; new insights into the mechanisms underlying cell differentiation and development; lessons from model organisms regarding organismal behavior; revelations regarding the dynamics of cell signaling pathways; increasing recognition of the ubiquity and complexity of ubiquitin and related molecules in signaling processes; and a family of channels that have cornered the market on peripheral sensory perception.

*Corresponding author. E-mail: eadler{at}

Citation: E. M. Adler, J. F. Foley, N. R. Gough, L. B. Ray, 2007: Signaling Breakthroughs of the Year. Sci. Signal. 1, eg1 (2008).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882