Focus Issue: From Input to Output—Are All Paths Equal?

Nancy R. Gough^*

Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: Science and Science Signaling team up to explore the properties of signaling networks. Science focuses on feedback loops, new techniques for detecting such processes, and how these influence signaling outcomes (http://www.sciencemag.org/cellsignaling08/). Science Signaling focuses on systems-level understanding of signaling networks with an emphasis on explaining how input signals are interpreted to generate various responses.

* Contact information. E-mail: ngough{at}aaas.org

The editors suggest the following Related Resources on Science sites:

In Science Signaling

RESEARCH RESOURCES
Systems Biology
The switches.ELM Resource: A Compendium of Conditional Regulatory Interaction Interfaces

Kim Van Roey, Holger Dinkel, Robert J. Weatheritt, Toby J. Gibson, and Norman E. Davey (2 April 2013)
Sci. Signal. 6 (269), rs7. [DOI: 10.1126/scisignal.2003345]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

RESEARCH ARTICLES
Computational Biology
Decoupling of Receptor and Downstream Signals in the Akt Pathway by Its Low-Pass Filter Characteristics

Kazuhiro A. Fujita, Yu Toyoshima, Shinsuke Uda, Yu-ichi Ozaki, Hiroyuki Kubota, and Shinya Kuroda (27 July 2010)
Sci. Signal. 3 (132), ra56. [DOI: 10.1126/scisignal.2000810]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

In Science Magazine

INTRODUCTION TO SPECIAL ISSUE
Getting Your Loops Straight

L. Bryan Ray (17 October 2008)
Science 322 (5900), 389. [DOI: 10.1126/science.322.5900.389]
 |  Summary »  |  PDF »