Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. STKE, 2 November 1999
Vol. 1999, Issue 6, p. tw5
[DOI: 10.1126/scisignal.61999tw5]

EDITORS' CHOICE

Cell growth Cell growth: A Single Bag of Tricks for Yeast

The already impressive capacity of yeast to use very similar Map kinase (MAPK) signaling pathways to mediate distinct biological processes becomes even more amazing with a report from Lee and Elion. The MAPKKK/Ste11 and other downstream components were thought to be dedicated to mating and invasive growth signaling pathways and to be inactive during normal vegetative growth. The authors show that Ste11 and other components shared by the mating and invasive growth pathway also function to promote vegetative growth. Hence, yeast appear to accommodate a variety of responses by using appropriate members from a single repertoire of signaling components.

Lee, B.N., and Elion, E.A. (1999) The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components. Proc. Natl. Acad. Sci. U.S.A. 96: 12679-12684. [Abstract] [Full Text]

Citation: Cell growth: A Single Bag of Tricks for Yeast. Sci. STKE 1999, tw5 (1999).

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882