Science Signaling Podcast: 28 July 2009

Michael B. Yaffe^1,2 and Annalisa M. VanHook³

¹ Chief Scientific Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
² David H. Koch Institute for Integrative Cancer Research, Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
³ Associate Online Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This is a conversation with Science Signaling's Chief Scientific Editor Micheal Yaffe about articles in the 28 July 2009 Focus Issue on complexity.

The editors suggest the following Related Resources on Science sites:

In Science Signaling

RESEARCH ARTICLES
Computational Biology
Cell Type–Specific Importance of Ras–c-Raf Complex Association Rate Constants for MAPK Signaling

Christina Kiel and Luis Serrano (28 July 2009)
Sci. Signal. 2 (81), ra38. [DOI: 10.1126/scisignal.2000397]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

RESEARCH ARTICLES
Computational Biology
Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases

Chris Soon Heng Tan, Bernd Bodenmiller, Adrian Pasculescu, Marko Jovanovic, Michael O. Hengartner, Claus Jørgensen, Gary D. Bader, Ruedi Aebersold, Tony Pawson, and Rune Linding (28 July 2009)
Sci. Signal. 2 (81), ra39. [DOI: 10.1126/scisignal.2000316]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

RESEARCH ARTICLES
Computational Biology
Integrating Proteomic, Transcriptional, and Interactome Data Reveals Hidden Components of Signaling and Regulatory Networks

Shao-shan Carol Huang and Ernest Fraenkel (28 July 2009)
Sci. Signal. 2 (81), ra40. [DOI: 10.1126/scisignal.2000350]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

EDITORIAL GUIDES
Computational Biology
Focus Issue: Unraveling Signaling Complexity

Nancy R. Gough and John F. Foley (28 July 2009)
Sci. Signal. 2 (81), eg10. [DOI: 10.1126/scisignal.281eg10]
 |  Abstract »  |  Full Text »  |  PDF »

PERSPECTIVES
Computational Biology
Understanding Modularity in Molecular Networks Requires Dynamics

Roger P. Alexander, Philip M. Kim, Thierry Emonet, and Mark B. Gerstein (28 July 2009)
Sci. Signal. 2 (81), pe44. [DOI: 10.1126/scisignal.281pe44]
 |  Abstract »  |  Full Text »  |  PDF »

PERSPECTIVES
Biochemistry
Proteomic Revelation: SUMO Changes Partners When the Heat Is On

Karin Flick and Peter Kaiser (28 July 2009)
Sci. Signal. 2 (81), pe45. [DOI: 10.1126/scisignal.281pe45]
 |  Abstract »  |  Full Text »  |  PDF »

PERSPECTIVES
Cell Biology
The Complexity of Cell Signaling and the Need for a New Mechanics

William S. Hlavacek and James R. Faeder (28 July 2009)
Sci. Signal. 2 (81), pe46. [DOI: 10.1126/scisignal.281pe46]
 |  Abstract »  |  Full Text »  |  PDF »

PERSPECTIVES
Cell Biology
Dynamic Advances in NF-B Signaling Analysis

Taeko Kobayashi and Ryoichiro Kageyama (28 July 2009)
Sci. Signal. 2 (81), pe47. [DOI: 10.1126/scisignal.281pe47]
 |  Abstract »  |  Full Text »  |  PDF »