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Sci. Signal., 10 November 2009
Vol. 2, Issue 96, p. pe71
[DOI: 10.1126/scisignal.296pe71]

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A New Mechanism of Phosphoregulation in Signal Transduction Pathways

Kirsten Jung* and Heinrich Jung

Munich Center of Integrated Protein Science (CIPSM), Ludwig-Maximilians-Universität München, Mikrobiologie, 82152 Martinsried, Germany.

Abstract: Histidine protein kinases and serine, threonine, or tyrosine protein kinases play essential roles in signal transduction in prokaryotes and eukaryotes. A third type of protein kinase, an arginine protein kinase, has been identified. McsB of Bacillus subtilis phosphorylates the heat shock transcriptional regulator CtsR and can be regarded as the founding member of arginine protein kinases.

* Corresponding author. E-mail, jung{at}lmu.de

Citation: K. Jung, H. Jung, A New Mechanism of Phosphoregulation in Signal Transduction Pathways. Sci. Signal. 2, pe71 (2009).

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CtsR Regulation in mcsAB-Deficient Gram-Positive Bacteria.
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