Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
GoGreen Membership

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Sci. STKE, 16 May 2000
Vol. 2000, Issue 32, p. tw8
[DOI: 10.1126/stke.2000.32.tw8]

EDITORS' CHOICE

DEVELOPMENTAL BIOLOGY Stuck Offside

Abstract:

The bilateral symmetry that is such a visible characteristic of higher animals is not without its exceptions--for example, in birds and mammals, the heart loops off to one side as it develops. The signaling events that establish this asymmetry seem to begin with the earliest stages of gastrulation. García-Castro et al. now demonstrate that N-cadherin, a molecule that generally mediates cell adhesion, is expressed at the right place and time in chick embryos to be one of the earliest mediators of left-right asymmetry. Thus, the processes that result in established asymmetry may include cell adhesion, as well as the already known signaling events.

García-Castro, M., Vielmetter, E., and Bronner-Fraser, M. (2000) N-Cadherin, a cell adhesion molecule involved in establishment of embryonic left-right asymmetry. Science 288: 1047-1051. [Abstract] [Full Text]

Citation: Stuck Offside. Sci. STKE 2000, tw8 (2000).

Read the Full Text

ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)