Sci. STKE, 4 July 2000
Plant Biology Perceiving Plant Steroids
Genome analysis of Arabidopsis and other plants has identified a family of proteins that share leucine-rich repeats and have other characteristics that suggest that they may be receptor-like kinases. He et al. now present an analysis of one family member, BRI1, previously implicated in brassinosteroid signaling. They worked with a fusion protein constructed from the extracellular domain from the Arabidopsis protein and the kinase domain from a receptor from rice that modulates disease resistance. They now show that the perception of the ligand, in this case a steroid, occurs through the extracellular domain of BRI1, at the cell surface.
He, Z., Wang, Z.-Y., Li, J., Zhu, Q., Lamb, C., Ronald, P., and Chory, J. (2000) Perception of brassinosteroids by the extracellular domain of the receptor kinase BRI1. Science 288: 2360-2363. [Abstract] [Full Text]
Citation: Perceiving Plant Steroids. Sci. STKE 2000, tw4 (2000).
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