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Sci. STKE, 11 July 2000
Vol. 2000, Issue 40, p. tw10
[DOI: 10.1126/stke.2000.40.tw10]

EDITORS' CHOICE

REVIEW PDZ Domains

Abstract:

Defined tertiary structures allow proteins to bind to and communicate with other proteins. The PDZ domain, identified in several signaling proteins located at the plasma membrane, binds to a (T/S)XV motif found in the COOH-terminus of other proteins. Garner et al. review the role of the PDZ domain in protein complex assembly in pre- and postsynaptic membranes, and the formation of signaling "active zones."

Garner, C.C., Nash, J. and Huganir, R.L. (2000) PDZ domains in synapse assembly and signalling. Trends Cell Biol. 10: 274-280. [Online Journal]

Citation: PDZ Domains. Sci. STKE 2000, tw10 (2000).

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Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)