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Sci. STKE, 18 July 2000
[DOI: 10.1126/stke.2000.41.pe1]

PERSPECTIVES

Cyclic ADP Ribose as a Calcium-Mobilizing Messenger

Antony Galione, and Grant C. Churchill

The authors are at the University of Oxford, Department of Pharmacology, Mansfield Road, Oxford OX1 3QT, UK.

Abstract:

This Perspective by Galione and Churchill is one in a series on intracellular calcium release mechanisms. The authors review the evidence for cyclic adenosine diphosphate ribose (cADPR) being a second messenger involved in regulating intracellular calcium. In addition, the physiological stimuli and responses mediated by cADPR are discussed. The Perspective is accompanied by a movie showing a calcium wave triggered by cADPR.

Citation:
Galione,A., Churchill,G. C. (2000) Cyclic ADP Ribose as a Calcium-Mobilizing Messenger.
Science's STKE: http://www.stke.org/cgi/content/full/OC_sigtrans;2000/41/pe1

© 2000 American Association for the Advancement of Science

Citation: A. Galione, G. C. Churchill, Cyclic ADP Ribose as a Calcium-Mobilizing Messenger. Sci. STKE 2000, pe1 (2000).

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