Sci. STKE, 18 July 2000
Cyclic ADP Ribose as a Calcium-Mobilizing Messenger
Antony Galione and Grant C. Churchill
The authors are at the University of Oxford, Department of Pharmacology, Mansfield Road, Oxford OX1 3QT, UK.
Abstract: This Perspective by Galione and Churchill is one in a series on intracellular calcium release mechanisms. The authors review the evidence for cyclic adenosine diphosphate ribose (cADPR) being a second messenger involved in regulating intracellular calcium. In addition, the physiological stimuli and responses mediated by cADPR are discussed. The Perspective is accompanied by a movie showing a calcium wave triggered by cADPR.
Citation: A. Galione, G. C. Churchill, Cyclic ADP Ribose as a Calcium-Mobilizing Messenger. Sci. STKE 2000, pe1 (2000).
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