Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Sci. STKE, 1 August 2000
Vol. 2000, Issue 43, p. pe1
[DOI: 10.1126/stke.2000.43.pe1]

PERSPECTIVES

The Informational Content of Gradients of Wnt Proteins

Alfonso Martinez Arias

The author is in the Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK. E-mail: ama11@cus.cam.ac.uk

Abstract: This perspective tackles the issues facing developmental biologists and cell biologists regarding how the molecular mechanisms for specifying cell fate are defined. This Perspective focuses on members of the Wnt family. The author proposes that Wnt proteins may act as stabilizing signals for earlier inductive events in certain systems, for example, in Caenorhabditis elegans during the migration of two neurons and in Drosophila melanogaster during the patterning of the wing.

Citation: A. Martinez Arias, The Informational Content of Gradients of Wnt Proteins. Sci. STKE 2000, pe1 (2000).

Read the Full Text



To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882