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Sci. STKE, 1 August 2000
Vol. 2000, Issue 43, p. pe1
[DOI: 10.1126/stke.2000.43.pe1]

PERSPECTIVES

The Informational Content of Gradients of Wnt Proteins

Alfonso Martinez Arias

The author is in the Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK. E-mail: ama11@cus.cam.ac.uk

Abstract:

This perspective tackles the issues facing developmental biologists and cell biologists regarding how the molecular mechanisms for specifying cell fate are defined. This Perspective focuses on members of the Wnt family. The author proposes that Wnt proteins may act as stabilizing signals for earlier inductive events in certain systems, for example, in Caenorhabditis elegans during the migration of two neurons and in Drosophila melanogaster during the patterning of the wing.

Citation:
Martinez Arias,A. (2000) The Informational Content of Gradients of Wnt Proteins.
Science's STKE: http://www.stke.org/cgi/content/full/OC_sigtrans;2000/43/pe1

© 2000 American Association for the Advancement of Science

Citation: A. Martinez Arias, The Informational Content of Gradients of Wnt Proteins. Sci. STKE 2000, pe1 (2000).

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Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)