Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Sci. STKE, 15 August 2000
Vol. 2000, Issue 45, p. pe1
[DOI: 10.1126/stke.2000.45.pe1]

Neuronal Signal Transduction Pathways: Wasteland or the Promised Land?

Bryan L. Roth

Departments of Psychiatry, Biochemistry, and Neuroscience, Case Western Reserve University, 11100 Euclid Avenue, Room W438, Cleveland, OH 44106, USA.

Review and commentary on Cerebral Signal Transduction: From First to Fourth Messengers, edited by Maarten E. A. Reith.
The Humana Press, Totowa, NJ, 2000. 440 pp. $125.00

Abstract: Proteins used in signal transduction pathways are commonly found in different cell types and organs. However, specific proteins whose expression is highly restricted are also utilized for allowing discrete responsiveness to signals that are otherwise ignored by other cells. How the brain uses common and specific signal proteins for communication within and beyond the cerebrum has been an area of intense study. A new book concentrates on the signaling that occurs in the brain under normal and pathological conditions--memory, apoptosis, neurodegeneration, depression, and drug dependence--and is filled with chapters written by experts in neurobiology and neurophysiology. Bryan Roth reviews the book and discusses in detail several chapters that may lead to promising future research.

Citation: B. L. Roth, Neuronal Signal Transduction Pathways: Wasteland or the Promised Land? Sci. STKE 2000, pe1 (2000).

Read the Full Text

Reduction of Cysteine Sulfinic Acid by Sulfiredoxin Is Specific to 2-Cys Peroxiredoxins.
H. A. Woo, W. Jeong, T.-S. Chang, K. J. Park, S. J. Park, J. S. Yang, and S. G. Rhee (2005)
J. Biol. Chem. 280, 3125-3128
   Abstract »    Full Text »    PDF »

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882