Sci. STKE, 29 August 2000
Immunology Imaging Immunological Synapses
Immunological synapses arise at contact zones between antigen-presenting cells and T cells. Synapses have distinct organization and are composed of T cell receptors interacting with major histocompatibility complex-peptide entities surrounded by various potentiating coreceptors and signaling molecules that migrate into the synapse through cytoskeleton-dependent processes. Krummel et al. have extended initial studies in lipid bilayers to explore the architecture and the extraordinary dynamics of immunological synapse formation by real-time video microscopy of whole cells containing green fluorescent protein chimeras.
Citation: Imaging Immunological Synapses. Sci. STKE 2000, tw10 (2000).
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