Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Signaling

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Sci. STKE, 26 September 2000
Vol. 2000, Issue 51, p. pe1
[DOI: 10.1126/stke.2000.51.pe1]

PERSPECTIVES

IP3 Receptor-Operated Calcium Entry

Katsuhiko Mikoshiba, and Mitsuharu Hattori

The authors are at the Division of Molecular Neurobiology, Institute of Medical Sciences, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan, and the Laboratory for Developmental Neurobiology, BSI, RIKEN, Wako, Saitama, 351-0198, Japan. E-mail: mikosiba{at}ims.u-tokyo.ac.jp

Abstract:

This Perspective by Mikoshiba and Hattori is the third in a series on cellular calcium release mechanisms. The authors describe the regulated release of calcium from intracellular stores by the inositol 1,4,5 trisphosphate receptor (IP3R) and the relationship of this release mechanism to calcium influx from the extracellular milieu through store-operated calcium channels. They discuss a model proposing that intracellular and plasma membrane calcium channels are functionally and physically coupled.

Citation:
Mikoshiba,K., Hattori,M. (2000) IP3 Receptor-Operated Calcium Entry.
Science's STKE: http://www.stke.org/cgi/content/full/OC_sigtrans;2000/51/pe1

© 2000 American Association for the Advancement of Science

Citation: K. Mikoshiba, M. Hattori, IP3 Receptor-Operated Calcium Entry. Sci. STKE 2000, pe1 (2000).

Read the Full Text

ADVERTISEMENT
Click Me!

ADVERTISEMENT

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)