Sci. STKE, 9 October 2001
Plant Biology Putting the Pieces Together
Plants respond to light with numerous changes in developmental and physiological processes. However, the exact process by which the light signal is transduced into developmental alterations has remained obscure. Using a variety of assays in Arabidopsis, Wang et al. demonstrate a physical interaction between the blue-light photoreceptors, cryptochromes, and COP1, a ubiquitin ligase that can promote degradation of proteins by the 26S proteasome. Among the proteins that can be targeted for destruction by the proteasome is HY5, which is a transcription factor that can bind to and regulate promoters of light-inducible genes. The demonstration of a physical connection between these components helps explain the signaling pathway by which blue light affects plant growth and development.
Citation: Putting the Pieces Together. Sci. STKE 2001, tw372 (2001).
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882