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Sci. STKE, 26 June 2001
Vol. 2001, Issue 88, p. tw4
[DOI: 10.1126/stke.2001.88.tw4]


Redox Sensing Redox Control of Growth

Prokaryotes sense change in environmental oxygen through a two-component signal transduction system and adjust their metabolism accordingly. Surprisingly, oxygen is not the molecular signal that regulates this process, which involves a membrane-associated sensor kinase and a response regulator that modulates gene expression. Georgellis et al. have determined that the redox state of membrane-bound quinones regulates the ArcB sensor kinase of the bacterium Escherichia coli; quinones are carriers in electron transport chains that are linked to metabolic reactions.

D. Georgellis, O. Kwon, E. C. C. Lin, Quinones as the redox signal for the Arc two-component system of bacteria. Science 292, 2314-2316 (2001). [Abstract] [Full Text]

Citation: Redox Control of Growth. Sci. STKE 2001, tw4 (2001).

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