Jump to: Page Content, Section Navigation, Site Navigation, Site Search, Account Information, or Site Tools.
Guest Alerts | Access Rights | My Account | Sign In
|
|
Sci. STKE, 4 September 2001 EDITORS' CHOICESTRUCTURAL BIOLOGY Maintaining Fluid HomeostasisAbstract: Natriuretic peptides are hormones that are involved in the regulation of fluid balance, with particular relevance for cardiovascular function and blood pressure. This family of peptides is recognized by a family of cell surface receptors (NPR-A, -B, and -C). He et al. have determined the crystal structures of the extracellular portion of NPR-C with and without natriuretic peptide C bound. One molecule of the peptide binds to a receptor dimer; binding appears to close the cleft between the monomers. X. He, D. Chow, M. M. Martick, K. C. Garcia, Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone. Science 293, 1657-1662 (2001). [Abstract] [Full Text]
Citation: Maintaining Fluid Homeostasis. Sci. STKE 2001, tw12 (2001). |
Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)