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Sci. STKE, 19 March 2002
Vol. 2002, Issue 124, p. pe13
[DOI: 10.1126/scisignal.1242002pe13]

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Argosomes: Intracellular Transport Vehicles for Intercellular Signals?

Jan L. Christian*

Department of Cell and Developmental Biology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA.

Abstract: Cell clusters in the immature tissues of developing organisms create morphogen gradients that guide cellular differentiation into specific cell fates. Although the process of simple diffusion in gradient establishment has been well studied, there are other mechanisms by which cells establish morphogen gradients. Christian discusses the recent findings that morphogens may establish gradients through the use of plasma membrane-containing exovesicles, termed "argosomes."

*Contact information. E-mail: christia{at}ohsu.edu

Citation: J. L. Christian, Argosomes: Intracellular Transport Vehicles for Intercellular Signals? Sci. STKE 2002, pe13 (2002).

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