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Sci. STKE, 2 April 2002
Vol. 2002, Issue 126, p. pe16
The Message and the Messenger: Delivering RNA in Neurons
Kenneth S. Kosik* and
Anna M. Krichevsky
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Synaptic plasticity results in enduring changes in synaptic function. Localized protein synthesis is part of this process. Kosik and Krichevsky describe how a dynamic macromolecular structure, the RNA granule, may be a key element contributing to changes in protein production leading to synaptic plasticity.
Frank Angenstein, Anne M. Evans, Robert E. Settlage, Stewart T. Moran, Shuo-Chien Ling, Anna Y. Klintsova, Jeffrey Shabanowitz, Donald F. Hunt, and William T. Greenough (15 October 2002) J. Neurosci.22 (20), 8827.
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