The Message and the Messenger: Delivering RNA in Neurons

Kenneth S. Kosik^* and Anna M. Krichevsky

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Summary: Synaptic plasticity results in enduring changes in synaptic function. Localized protein synthesis is part of this process. Kosik and Krichevsky describe how a dynamic macromolecular structure, the RNA granule, may be a key element contributing to changes in protein production leading to synaptic plasticity.

*Corresponding author. E-mail: kosik{at}rics.bwh.harvard.edu

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