Sci. STKE, 19 November 2002
Neuroscience Epilepsy and Excitation Explored
Human temporal lobe epilepsy is a severe and potentially life-threatening disorder. Cohen et al. (see the Perspective by Köhling) recorded from neurons in specimens from epileptic patients who had undergone surgery for treatment of the disease. In a brain area called the subiculum, they observed synchronous discharges reminiscent of the patients' EEG records. In a subpopulation of pyramidal neurons from this area, GABAergic input was not inhibitory but rather depolarizing and therefore excitatory.
Citation: Epilepsy and Excitation Explored. Sci. STKE 2002, tw432 (2002).
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