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Sci. STKE, 10 December 2002
Vol. 2002, Issue 162, p. pe50
[DOI: 10.1126/stke.2002.162.pe50]

PERSPECTIVES

Plasticity of the Kinomes in Monkey and Rat Tissues

Steven Pelech1,2* and Hong Zhang1

1Kinexus Bioinformatics Corporation, Vancouver, BC, Canada.
2Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

Abstract: The Kinetworks KPKS 1.0 immunoblotting screen was used to investigate the differential expression of 58 protein serine-threonine kinases, five protein threonine-tyrosine kinases, and 15 other nonreceptor protein tyrosine kinases in three types of human blood cells, 14 monkey organs, and six rat organs. The results demonstrate striking differences in the kineome profiles of diverse organs and even between the same organs in different species.

*Corresponding author. Kinexus Bioinformatics Corporation, Suite 401, 2389 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z4. Telephone, 604-822-9966; fax, 604-822-9964; e-mail: spelech{at}kinexus.ca

Citation: S. Pelech, H. Zhang, Plasticity of the Kinomes in Monkey and Rat Tissues. Sci. STKE 2002, pe50 (2002).

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