Sci. STKE, 28 January 2003
Longevity Live Lean, Live Long
Restricting food generally increases the life-span of mammals, and this effect may be related to the decrease in caloric intake or to the accompanying reduction in fat mass. Studying genetically modified mice that eat normally but cannot properly store energy in fat, Blüher et al. show that leanness alone is associated with a modest (18%) increase in mean life-span, possibly through effects on insulin signaling.
Citation: Live Lean, Live Long. Sci. STKE 2003, tw46 (2003).
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