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Sci. STKE, 11 February 2003
Vol. 2003, Issue 169, p. pe5
[DOI: 10.1126/stke.2003.169.pe5]


A Long Search for Glut4 Activation

Konstantin V. Kandror*

Boston University School of Medicine, Boston, MA 02118, USA.

Abstract: Insulin stimulates glucose transport in its target cells by translocation of the glucose transporter isoform 4 (Glut4) from an intracellular storage pool to the plasma membrane. A large body of evidence indicates that activity of Glut4 at the plasma membrane may vary. Recent findings suggest that p38 MAPK may be involved in regulation of the intrinsic activity of the transporter.

*Contact information. Telephone, 617-638-5049; fax, 617-638-5339; e-mail, kandror{at}

Citation: K. V. Kandror, A Long Search for Glut4 Activation. Sci. STKE 2003, pe5 (2003).

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A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression.
C. L. Buller, R. D. Loberg, M.-H. Fan, Q. Zhu, J. L. Park, E. Vesely, K. Inoki, K.-L. Guan, and F. C. Brosius III (2008)
Am J Physiol Cell Physiol 295, C836-C843
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