Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. STKE, 24 June 2003
Vol. 2003, Issue 188, p. tw243
[DOI: 10.1126/stke.2003.188.tw243]


PLANT BIOLOGY An Autonomous Flowering Pathway with an Autoregulator

Flowering time of plants can be controlled by pathways responsive to light or temperature, or through an autonomous pathway. The autonomous pathway promotes flowering and is especially important for Arabidopsis ecotypes that are rapid cyclers, that is, they will complete a life-cycle of vegetative and reproductive growth more than once a growing season. Quesada et al. show that an RNA-binding protein with a WW domain, FCA, which promotes flowering, regulates its own production by promoting usage of an upstream polyadenylation site located in an alternatively spliced third intron, leading to the production of truncated forms of FCA that are not functional in regulating flowering. Only intronless versions of FCA could be overexpressed, and these suppressed expression of the native, functional {gamma} transcript and promoted the accumulation of the truncated β transcript. Expression of another truncated version that lacks the WW domain, the FCA-{delta}, did not alter the abundance of FCA or the pattern of transcripts produced. Thus, the WW domain is essential for the autoregulatory activity of FCA. Overexpression of the intronless FCA-{gamma} transcript resulted in premature flowering and in transgenic plants expressing the highest levels of FCA-{gamma}. Additional phenotypes were observed, including small stature, premature senescence and death of leaves. The authors propose that autoregulation may prevent premature flowering.

V. Quesada, R. MacKnight, C. Dean, G. G. Simpson, Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time. EMBO J. 22, 3142-3152 (2003). [Abstract] [Full Text]

Citation: An Autonomous Flowering Pathway with an Autoregulator. Sci. STKE 2003, tw243 (2003).

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882