|
Sci. STKE, 15 July 2003 PERSPECTIVESA Kelch ß Propeller Featuring as a Gß Structural Mimic: Reinventing the Wheel?Jan Gettemans*, Kris Meerschaert, Joël Vandekerckhove, and Veerle De Corte Department of Biochemistry, Faculty of Medicine and Health Sciences, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University, Rommelaere Institute, Albert Baertsoenkaai 3, B-9000 Ghent, Belgium. Summary:
New genetic and protein interaction data suggest that G protein *Corresponding author: Telephone, 00 32 9 33 13340; fax, 00 32 9 33 13597; e-mail, jan.gettemans{at}UGent.be
Citation: J. Gettemans, K. Meerschaert, J. Vandekerckhove, V. De Corte, A Kelch ß Propeller Featuring as a Gß Structural Mimic: Reinventing the Wheel? Sci. STKE 2003, pe27 (2003). The editors suggest the following Related Resources on Science sites:In Science Signaling
|
subunits may have partners with primary sequences that are quite divergent. How this is achieved may be through the adoption of similar structures, the ß propeller, by both proteins containing WD-40 repeats and kelch domains. Gettemans et al. describe results in yeast that suggest that kelch-domain proteins may serve as previously unrecognized ß subunits in the heterotrimeric G protein complex.
Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)
Magazine | News | Signaling | Careers | Multimedia | Collections | Help | Site Map | RSS
Subscribe | Feedback | Privacy / Legal | About Us | Advertise With Us | Contact Us
© 2003 American Association for the Advancement of Science. All Rights Reserved.
AAAS is a partner of HINARI, AGORA, PatientInform, CrossRef, and COUNTER.
You have reached the bottom of the page. Back to top