Sci. STKE, 26 August 2003
PLANT BIOLOGY Overcoming Negatives in Auxin Regulation
The plant hormone auxin is a key regulator of growth and development. Zhao et al. identified a compound, sirtinol, that stimulates biological responses similar to those initiated by auxin. They then screened for mutants of Arabidopsis that did not respond to sirtinol and identified a mutant they called sir1 that encodes a protein with similarity to a ubiquitin-activating E1-like protein. This result may help explain how auxin can rapidly degrade negative regulators as part of its mechanism of action.
Citation: Overcoming Negatives in Auxin Regulation. Sci. STKE 2003, tw336 (2003).
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