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Sci. STKE, 21 October 2003
Vol. 2003, Issue 205, p. tw416
[DOI: 10.1126/scisignal.2052003tw416]

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IMAGING Glycine Receptors On the Move

Semiconductor quantum dots (QDs) have recently emerged as probes with the potential to revolutionize fluorescence imaging. Dahan et al. have now detected single QD-tagged glycine receptors in living cultured spinal neurons. By combining in vivo monitoring and post hoc electron microscopic analysis, the dynamics of receptors was monitored over time and the entry of a receptor into the synapse was directly observed.

M. Dahan, S. Lévi, C. Luccardini, P. Rostaing, B. Riveau, A. Triller, Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science 302, 442-445 (2003). [Abstract] [Full Text]

Citation: Glycine Receptors On the Move. Sci. STKE 2003, tw416 (2003).

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