Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Career Fair

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Sci. STKE, 10 February 2004
Vol. 2004, Issue 219, p. tw56
[DOI: 10.1126/stke.2192004TW56]

EDITORS' CHOICE

GENETICS Genome-Wide Functional Analysis

An RNA interference-based screen on a genome-wide scale is likely to become one of the methods of choice for comprehensive functional genomic analysis because of its potential to identify, rapidly and systematically, genes that control a variety of cellular processes. Boutros et al. conducted such a screen of the Drosophila genome in tissue culture cells and identified new genes and orthologs of human disease genes that control cell growth and survival. The results provide new functional information for annotating the genome of this important model organism.

M. Boutros, A. A. Kiger, S. Armknecht, K. Kerr, M. Hild, B. Koch, S. A. Haas, Heidelberg Fly Array Consortium, R. Paro, N. Perrimon, Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303, 832-835 (2004). [Abstract] [Full Text]

Citation: Genome-Wide Functional Analysis. Sci. STKE 2004, tw56 (2004).

ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)