Sci. STKE, 22 June 2004
TRANSCRIPTION Optimized Noise in Gene Expression
Phenotypic variability may contribute to the evolution of a species. Raser and O'Shea now measure variability in gene expression, sometimes known as noise, in yeast. Noise was gene-specific and controlled by the balance between promoter activation and transcription. Two types of noise were examined: intrinsic noise, which occurs during gene expression, and extrinsic noise, which can be caused by cell heterogeneity or signal transduction events.
Citation: Optimized Noise in Gene Expression. Sci. STKE 2004, tw222 (2004).
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882